Description

Anti USAG-1 (USAG1/SOSTDC1 Recombinant Protein Antigen )

The Anti USAG-1 (USAG1/SOSTDC1) Recombinant Protein Antigen from Novus Biologicals, part of Bio-Techne, is a high-quality E. coli-derived recombinant protein designed for antibody competition assays. It features an N-terminal His6-ABP tag and exhibits >80% purity by SDS-PAGE and Coomassie staining, making it ideal for confirming antibody specificity in research applications.

Key Features & Benefits

• High-purity recombinant protein antigen (>80% by SDS-PAGE)
• N-terminal His6-ABP tag for enhanced binding and detection
• Specifically designed for antibody competition assays
• E. coli-expressed for consistent quality and reproducibility
• Predicted molecular weight: 28 kDa (may vary due to PTMs or cleavage)
• Formulated in PBS with 1 M Urea, pH 7.4, preservative-free
• Shipped with polar packs; store at -20 °C and avoid repeated freeze-thaw cycles

Applications

• Antibody competition assays (10–100 molar excess)
• Confirm antibody specificity for USAG1/SOSTDC1 (Catalog # NBP3-17959)
• Research on BMP signaling pathways, cellular proliferation, differentiation, and apoptosis
• In vitro functional studies of SOSTDC1 interactions

Specifications

Background

SOSTDC1, also known as USAG1, WISE, or Ectodin, is a secreted protein containing a C-terminal cystine knot-like domain. It functions as a bone morphogenetic protein (BMP) antagonist, binding BMPs and preventing their receptor interactions. This regulation of BMP signaling is critical for controlling cellular proliferation, differentiation, and apoptosis in multiple tissues.

Notes

This product is intended strictly as a blocking antigen for antibody competition assays. Any other use is at the user’s risk, and commercial production is prohibited. Please contact technical support for lot-specific concentration and availability.

Product Datasheet:

CLICK HERE

The Antigen Blocking Protocol:

CLICK HERE

Safety Datasheet (SDS):

CLICK HERE

Certificate of Analysis

To receive a Certificate of Analysis, please send us the lot number to info@dentinova.co.uk after purchasing.

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