Description

Myricetin 98% – ENPP1 Inhibitor for Tissue Healing (Research Use Only)

A Potent Flavonoid for Regenerative, Anti-Inflammatory, and Molecular Pathway Studies

Myricetin (98%) is a high-purity, research-grade flavonoid compound widely investigated for its ENPP1 inhibitory activity, antioxidant capacity, and role in tissue regeneration pathways. With a well-defined molecular structure and strong bioactive profile, Myricetin is increasingly utilized in biomaterials, regenerative medicine, and molecular signaling research, including emerging applications in dental tissue healing and mineralization control.

This compound is supplied as a crystalline solid with ≥98% purity, ensuring reliable reproducibility and consistency for laboratory and preclinical research.

⚠️ This product is for Research Use Only (RUO): Not for human or clinical use

Myricetin Molecular Identity & Chemical Specifications

Myricetin is a naturally occurring polyphenolic flavonoid with a strong profile in biochemical modulation and oxidative stress control.

Key Chemical Data:

• CAS Number: 529-44-2
• Molecular Formula: C₁₅H₁₀O₈
• Molecular Weight: 318.24 g/mol
• Purity: ≥98%
• Physical Form: Brown-yellow crystalline solid
• Melting Point: >300°C
• IUPAC Name: 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one

Its multi-hydroxyl structure contributes to strong free radical scavenging and enzyme interaction capabilities, making it highly relevant for biochemical pathway modulation studies.

Myricetin Mechanism of Action: ENPP1 Inhibition & Regenerative Potential

Myricetin has gained attention as a potential ENPP1 inhibitor, a key enzyme involved in:

• Regulation of extracellular pyrophosphate (PPi)
• Inhibition of pathological calcification
• Control of mineralization processes

Why ENPP1 Inhibitor ( Myricetin  ) Matters in Tissue Healing

ENPP1 acts as a molecular “brake” on mineralization and regeneration. Inhibition of this pathway is being explored for:

• Enhanced bone and dentin regeneration
• Improved biomaterial integration
• Modulation of calcification-related disorders

Myricetin’s interaction with ENPP1 makes it a promising molecule for:

• Dental tissue engineering research
• Bone regeneration studies
• Biomaterial functionalization strategies

Broad Biological Activity Profile of Myricetin

Beyond ENPP1 inhibition, Myricetin demonstrates a wide range of bioactive properties:

Antioxidant Activity

• Strong free radical scavenger
• Protects cells from oxidative stress damage
• Supports studies in cell survival and regeneration

Anti-Inflammatory Effects

• Modulates inflammatory pathways
• Useful in chronic inflammation research models

Enzyme Inhibition

Myricetin98% has shown inhibitory activity against:

• α-glucosidase (metabolic research)
• Glyoxalase I (cellular detox pathways)
• Xanthine oxidase (oxidative stress regulation)

Neuroprotective Potential

• Demonstrated cell-protective effects in neuronal models
• Relevant for oxidative injury and degeneration studies

Applications of Myricetin in Research & Biomaterials

Myricetin (98%) is suitable for a wide range of laboratory and preclinical applications, including:

• ENPP1 inhibition studies
• Tissue regeneration and mineralization research
• Dental biomaterials and pulp-dentin healing models
• Anti-inflammatory and oxidative stress research
• Cancer and metabolic pathway studies
• Drug delivery and cocrystal formulation research

Its cell-permeable nature enhances its value in in vitro and molecular studies, enabling efficient interaction with intracellular targets.

Solubility & Handling

• Soluble in:
  • Dimethyl sulfoxide (DMSO)
  • Dimethyl formamide (DMF)
  • Ethanol
• Insoluble in:
  • Water

Storage Conditions

• Store at -20°C for long-term stability
• Protect from light and heat exposure
• Avoid contact with strong oxidizing agents

Proper handling ensures compound integrity and reproducibility of results.

Safety & Research Considerations

• Intended Use: Research Use Only (RUO)
• Not for human consumption or clinical application
• May cause irritation or hypersensitivity upon contact
• Use appropriate PPE (gloves, lab coat, eye protection)

Key Features at a Glance

• ≥98% high-purity research-grade compound
• Potent ENPP1 inhibitor candidate
• Strong antioxidant and anti-inflammatory properties
• Relevant for tissue healing and biomaterial research
• Well-characterized chemical profile
• Compatible with multiple solvent systems
• Reliable performance in in vitro studies

Why Choose Myricetin 98% for Research?

Myricetin stands out as a multifunctional bioactive molecule bridging biochemistry, regenerative medicine, and dental research.

Key Advantages:

• Targets critical pathways in mineralization and healing
• Supports cutting-edge ENPP1-related research
• Offers broad applicability across disciplines
• High purity ensures experimental reliability

For researchers exploring next-generation regenerative strategies, Myricetin provides a powerful, versatile, and scientifically validated tool.

Certificate of Analysis: Click to View the COA

Safety Data Sheets:

1- Catalogue J60450.MA: English, French, German,  Italian, Spanish

2- Catalogue  J60450.MB: English, French, German, Italian, Spanish

3- Catalogue J60450.MF: English, French, German, Italian, Spanish

Conclusion

Myricetin (98%) is a high-value research compound with significant relevance in ENPP1 inhibition, oxidative stress modulation, and tissue regeneration pathways. Its unique biochemical profile and versatility make it an essential molecule for advancing research in dental healing, biomaterials, and regenerative medicine. Available now at Dentinova Store.

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